The article about scientists here have found that mini- molecules called micro RNA may play a critical role in the progression of chronic myelitis leukemia from its more treatable chronic phase to a life-threatening phase, called blast crisis. They discovered an entirely new function for these molecules. The researchers show that micro RNAs can sometimes directly control a protein's function -not just whether or not the protein is made by the cell , as has been believed.Another thing study using cells from (CML) patients in blast crisis, suggest that certain progenitor white blood cells are kept from maturing when levels of one micro RNA, called miR-328. the finding are presented at 2007 annual meeting of the American society of hematology." say Principal investigator Danilo Perrotti, assistant professor of molecular virology, immunology and medical genetics and a researcher with the Ohio state university comprehensive cancer center.In case , a micro RNA called MIR-328 binds with a protein that, in phase CML, prevent imature blood cells from maturing. The MIR- 328 acts as a decoy molecule that normally ties up the protein.My feelling would be excellent aout scientists discover new role for miRNA in ieukemia
